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. Author manuscript; available in PMC: 2017 Mar 22.
Published in final edited form as: Immunol Cell Biol. 2016 Sep 21;95(3):261–271. doi: 10.1038/icb.2016.95

Figure 3. Combined c-REL and RELA deficiency impairs BAFF-mediated cell survival.

Figure 3

(left) Flow cytometric analysis of BAFF-stimulated purified B-cells from relfl/flrelafl/flCD19-Cre and CD19-Cre mice at d3 for DNA content by propidium iodide (PI) staining and summary of the corresponding percentage sub-G1 (bottom), and (right) for apoptotic/dead cells by annexin V/7AAD staining and summary of the corresponding percentage of annexin V/7AAD+ cells (bottom). Data are cumulative from independent experiments (n=4 per group), with each symbol representing a mouse. Data are shown as mean ± standard deviation. Statistical significance was determined by Student's t test (***, P<0.001).