Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 16;17:75–87. doi: 10.1016/j.ebiom.2017.02.013

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 2 — PIO lefts RC activity in the skeletal muscle and cerebellum unchanged but inversely modifies glycaemia in WT and Hq mice.

(A) Activity of RC CI activity of muscle homogenate in untreated (black open squares) and PIO-treated (green open squares) WT mice and untreated (black circle) and PIO-treated (green circles) Hq mice. The activity is either expressed as mg protein (absolute activity; left panel) or ratioed to complex V (right panel). (B) CI activity of cerebellum homogenate in untreated (black open squares) and PIO-treated (green open squares) WT and untreated (black circles) and PIO-treated (green circles) Hq mice. The activity is either expressed as mg protein (absolute activity; left panel) or ratioed to complex V (right panel). (C) Bi-monthly follow-up of glycaemia of ad libidum fed untreated (black open square) and PIO-treated (green open square) WT and untreated (black circles) and PIO-treated (green circles) Hq mice (left panel). (D) Opposite changes of glycaemia triggered by 5 month PIO-treatment in WT (squares) and Hq (circles). Biochemical analyses, glycaemia determination and statistical tests as described under Materials and Methods.