Table 4.
Clinical characteristics | Definition | Points |
Hypertension | Systolic blood pressure > 160 mmHg | 1 |
Abnormal liver or renal function | Chronic liver disease (e.g., cirrhosis) or biochemical evidence of significantly impaired liver function (e.g., bilirubin > 2 times the ULN plus one or more liver enzymes > 3 times the ULN | 1 or 2 |
Chronic dialysis, renal transplantation, or serum creatinine ≥ 200 micromol/L | ||
Stroke | Previous history of stroke | 1 |
Bleeding tendency or predisposition | Bleeding disorder or previous bleeding episode requiring hospitalization or transfusion | 1 |
Labile INRs | Labile INRs in patients taking warfarin | 1 |
(failure to maintain a therapeutic range at least 60% of the time) | ||
Elderly | Age > 65 years | 1 |
Drugs | Concomitant antiplatelet agents or NSAIDs | 1 or 2 |
Excessive alcohol use (≥ 8 units per week) |
Maximum score is 9. ULN: Upper limit of normal; INR: International normalized ratio; NSAIDs: Non-steroidal anti-inflammatory drugs.