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. 2017 Mar 21;23(11):1990–2001. doi: 10.3748/wjg.v23.i11.1990

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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Representative histopathological images of a tumor specimen with Ki-67 staining (first row), TUNEL staining (second row), CD31 staining (third row) and hematoxylin and eosin staining (fourth row) at baseline, day 3, day 7, day 14 and day 21 after treatment in the treated group. Brown staining in the Ki-67 images indicates cells in the proliferative state. Brown staining in the TUNEL images indicates cells undergoing apoptosis. Brown staining in the CD31 images indicates endothelial cells. Viable tumor tissues and necrosis were identified on HE stainings. HE: Hematoxylin and eosin.