Table 3.
Statistic comparisons of DNA Fragmentation Index and oxidative biomarkers between controls and infertile men
Parameters | Controls (n = 50) | OAT (n = 40) | Terato (n = 31) | Astheno (n = 29) | P-value | ||
---|---|---|---|---|---|---|---|
Controls vs OAT | Controls vs Terato | Controls vs Astheno | |||||
DFI (%) | |||||||
Means ± SD | 12.23 ± 4.73 | 28.88 ± 5.87 | 20.62 ± 4.42 | 25.18 ± 6.13 | P < 0.001 | P < 0.001 | P < 0.001 |
Min-Max | 0–23.40 | 16.41–44.80 | 10.80–28.41 | 12.24–49.01 | |||
SOD (×10−3 g/P) | |||||||
Means ± SD | 2.75 ± 0.97 | 1.09 ± 0.53 | 2.17 ± 1.31 | 2.10 ± 0.60 | P < 0.001 | 0.02 | 0.003 |
Min-Max | 1.02–7.99 | 0.44–6.76 | 0.91–6.76 | 0.71–3.41 | |||
GPX (×10−3 g/P) | |||||||
Means ± SD | 9.58 ± 2.44 | 3.89 ± 2.21 | 9.56 ± 2.81 | 8.79 ± 2.31 | P < 0.001 | NS | NS |
Min-Max | 3.21–20.65 | 0.11–7.83 | 0.98–15.03 | 2.21–9.87 | |||
CAT (×10−5 g/P) | |||||||
Means ± SD | 2.49 ± 1.46 | 1.89 ± 0.81 | 1.97 ± 0.71 | 2.30 ± 0.97 | 0.001 | NS | NS |
Min-Max | 0.65–10.80 | 0.01–6.43 | 0.80–3.65 | 0.43–2.99 | |||
MDA (μmol/l) | |||||||
Means ± SD | 1.54 ± 0.68 | 2.91 ± 1.15 | 2.19 ± 0.72 | 2.39 ± 1.79 | P < 0.001 | P < 0.001 | 0.03 |
Min-Max | 0.43–2.99 | 0.65–5.77 | 0.59–4.54 | 1.03–10.80 |
OAT Oligoasthenoteratozoospermics, Terato Teratozoospermics, Astheno asthenozoospermics, DFI DNA Fragmentation Index, SOD superoxide dismutase, GPX glutathione peroxidase, CAT Catalase, MDA Malondialdehyde acid, Max maximum, Min minimum, SD standard deviation, NS Not significant. Data are expressed as means ± SD. P ≤ 0.05 = significant; P ≤ .001 = highly significant