Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 22;8:99. doi: 10.3389/fneur.2017.00099

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Monje, Cicvaric, Acevedo Aguilar, Elbau, Horvath, Diao, Glat and Pollak.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Circadian period (tau), wheel-running activity, bout analysis, and phase shift response under free-running (dark/dark) conditions in interleukin (IL)-6 knockout (IL-6 KO) and wild-type (WT) mice. Analysis of the free-running circadian behavioral locomotor activity in IL-6 KO and WT mice (n = 9–11 per group) demonstrating comparable (A) tau and wheel-running activity during the (B) alpha and (C) rho phase and in (D) total amounts. (E) Significantly increased quantity of activity bouts in IL-6 KO compared with WT mice with unaltered (F) bout length and (G) activity counts/bout. (H) Unaltered phase shift response to a brief light pulse at CT14 is in IL-6 KO mice. All data are displayed as mean ± SEM; *p < 0.05.