Table 5.
Differentially expressed genes in invasive versus non-invasive corticotrophinomas.
| Gene symbol | Fold change | Gene symbol | Fold change | Gene symbol | Fold change | Gene symbol | Fold change |
|---|---|---|---|---|---|---|---|
| IFI44 | 43.02 | GPNMB | 2.76 | JAKMIP1 | −2.29 | ADD2 | −3.54 |
| ZNF676 | 29.28 | VSIG1 | 2.76 | JPH3 | −2.29 | TCF7L2 | −3.59 |
| CCND2 | 27.61 | SLC39A8 | 2.75 | FAXC | −2.31 | MYCN | −3.73 |
| ANGPTL7 | 15.2 | IRAK4 | 2.59 | CCDC88A | −2.33 | C14orf132 | −3.94 |
| ZNF208 | 13.55 | BBS10 | 2.58 | CERCAM | −2.33 | GNAO1 | −3.95 |
| ABRACL | 11.87 | TMEM63A | 2.52 | NAP1L5 | −2.36 | DACH2 | −4.04 |
| ALDH1A1 | 10.95 | TLCD1 | 2.51 | PRPF19 | −2.39 | LONRF2 | −4.05 |
| KCNH8 | 10.36 | TMEM55A | 2.34 | CLIP4 | −2.45 | FXYD5 | −4.09 |
| MGARP | 8.7 | MIOS | 2.33 | CAMK1 | −2.46 | CAMKV | −4.1 |
| SLC7A2 | 7.35 | CRLS1 | 2.28 | ID 2622970 | −2.49 | SULT4A1 | −4.16 |
| KIAA0040 | 7.11 | FER | 2.26 | KIF5A | −2.5 | KCNIP2 | −4.26 |
| CA10 | 7.06 | ASPH | 2.23 | MAGEE1 | −2.51 | DKK3 | −4.28 |
| DHCR24 | 6.87 | EFHA2 | 2.22 | RXRA | −2.57 | PTPRJ | −4.29 |
| PRKD3 | 6.81 | ZFYVE16 | 2.2 | ARNT2 | −2.61 | SCN1B | −4.29 |
| CCL28 | 6.43 | BRD9 | 2.19 | BAIAP3 | −2.62 | CALY | −4.33 |
| CDKN1B | 5.87 | MTRF1 | 2.19 | AKAP12 | −2.68 | CD200 | −4.56 |
| BDH2 | 5.8 | WDYHV1 | 2.17 | SCAMP5 | −2.69 | DTX1 | −4.66 |
| CEP85L | 5.77 | ZDHHC11 | 2.16 | SLC4A3 | −2.69 | ID 2667243 | −4.67 |
| CALML4 | 5.55 | SMC6 | 2.15 | DGKH | −2.7 | SLC1A2 | −4.88 |
| SCML1 | 5.33 | ADAM28 | 2.1 | CCDC136 | −2.71 | DIRAS1 | −4.97 |
| SLC28A3 | 5.11 | RBAK | 2.06 | RIMBP2 | −2.74 | RYR2 | −5.5 |
| STK3 | 4.78 | BRCC3 | 2.05 | CNNM1 | −2.75 | TUBB4A | −5.52 |
| FAM13A | 4.25 | TGS1 | 2.05 | GABBR1 | −2.76 | ELMOD1 | −5.75 |
| INPP5J | 4.24 | GGCT | 2.04 | STARD10 | −2.79 | FGD5 | −6.16 |
| PDLIM1 | 4.14 | CDKN2A | −2.01 | EIF4E3 | −2.8 | TAGLN3 | −6.39 |
| SLC43A1 | 4.14 | PRKACB | −2.02 | TMEM54 | −2.81 | RGS7 | −6.48 |
| ZNF680 | 3.79 | ID 615892 | −2.07 | KLHL23 | −2.94 | DOCK11 | −7.17 |
| PON2 | 3.71 | KCNB1 | −2.08 | N4BP2L1 | −2.95 | ATCAY | −7.18 |
| NUPR1 | 3.63 | KIF3C | −2.09 | PHOSPHO2-KLHL23 | −2.96 | KCND3 | −7.65 |
| PEX2 | 3.57 | PIGZ | −2.1 | ECE2 | −3.01 | DAPK1 | −7.8 |
| SEPP1 | 3.36 | NGFRAP1 | −2.11 | NISCH | −3.03 | CSGALNACT1 | −8.2 |
| NIN | 3.23 | MEF2A | −2.12 | SYT7 | −3.03 | CAV1 | −9.03 |
| CARD16 | 3.11 | FAM19A5 | −2.14 | CRAT | −3.04 | NAALAD2 | −9.34 |
| PAQR8 | 3.05 | RAB15 | −2.14 | GPRASP1 | −3.04 | MPPED2 | −9.51 |
| FCHO2 | 3.02 | RUNDC3A | −2.15 | KIAA0930 | −3.04 | ELAVL3 | −9.7 |
| SLC25A13 | 3.02 | TMEM179 | −2.17 | NAP1L3 | −3.06 | GHSR | −10.13 |
| CYP39A1 | 3 | PDK2 | −2.2 | TIMP2 | −3.07 | ID 3063035 | −10.29 |
| SLC16A9 | 2.96 | KIF6 | −2.23 | GPRASP2 | −3.26 | PPP1R17 | −10.81 |
| STK35 | 2.93 | CELF6 | −2.26 | FAM171B | −3.29 | SEPT3 | −11.83 |
| FAS | 2.91 | SNCB | −2.26 | FAIM2 | −3.3 | C11orf87 | −19.63 |
| AP1G2 | 2.89 | AGBL4 | −2.27 | FHL1 | −3.33 | VAT1L | −23.83 |
| CA13 | 2.82 | ID 933392 | −2.28 | RAPGEF4 | −3.33 | SEZ6L | −49.33 |
ANOVA p-value <0.05; fold change cut off = 2; false discovery rate <0.05; ID, transcript ID, no gene symbol available.