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. 2017 Mar 22;8:55. doi: 10.3389/fendo.2017.00055

Table 6.

Twenty most significantly over- or underexpressed genes in invasive versus non-invasive corticotrophinoma groups.

Gene symbol Description Fold change (linear) ANOVA FDR

p-Value p-Value
IFI44 Interferon-induced protein 44 43.02 0.00012 0.025879
CCND2 Cyclin D2 27.61 0.00003 0.013711
ZNF676 Zinc-finger protein 676 29.28 0.000198 0.030477
ANGPTL7 Angiopoietin-like 7 15.20 0.000035 0.015151
KCNH8 Potassium voltage-gated channel member 8 10.36 0.000554 0.045037
MGARP NADH dehydrogenase (ubiquinone) 1 8.70 0.00004 0.015427
DHCR24 24-dehydrocholesterol reductase 6.87 7.97E−07 0.004751
PRKD3 Protein kinase D3 6.81 0.000105 0.024751
CEP85L Centrosomal protein 85kda-like 5.77 0.000026 0.013222
SPON1 Spondin 1. Extracellular matrix protein −16.79 0.011393 0.16522
SEPT3 Septin 3 −11.83 0.00009 0.022919
MPPED2 Metallophosphoesterase domain-containing 2 −9.51 0.000086 0.022798
CSGALNACT1 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 −8.20 0.000234 0.031613
DAPK1 Death-associated protein kinase 1 −7.80 0.000037 0.015151
DOCK11 Dedicator of cytokinesis 11 −7.17 0.000299 0.034763
RGS7 Regulator of G protein signaling 7 −6.48 0.00001 0.010564
PEX2 Peroxisomal biogenesis factor 2 −3.57 0.0006 0.046209
TIMP2 TIMP metallopeptidase inhibitor 2 −3.07 0.000178 0.029718
ARNT2 Aryl-hydrocarbon receptor nuclear translocator 2 −2.61 0.000011 0.011139
CDKN2A Cyclin-dependent kinase inhibitor 2A −2.01 0.000344 0.035806

FDR, false discovery rate.