Table 2.

Trends of fluconazole non-susceptible (Flu NS) rate among C. tropicalis isolates by wards and specimen types during 5 years.

Characters	Overall		CHIF-NET10		CHIF-NET11		CHIF-NET12		CHIF-NET13		CHIF-NET14		P valuea
	n	Flu NS%	n	Flu NS%	n	Flu NS%	n	Flu NS%	n	Flu NS%	n	Flu NS%
Overall	507	23.1	89	11.2	108	11.1	115	16.5	92	34.8	103	42.7	<0.001
WARDS
Outpatient/Emergency	36	22.2	7	14.3	8	25.0	9	0.0	7	42.9	5	40.0	NDb
Inpatient	471	23.1	82	11.0	100	10.0	106	17.9	85	34.1	98	42.9	<0.001
Surgery	125	20.0	25	4.0	22	4.5	30	16.7	21	38.1	27	37.0	0.004
Internal medicine	147	21.8	23	8.7	35	11.4	27	18.5	33	36.4	29	31.0	0.049
Intensive care unit	169	25.4	31	19.4	36	11.1	40	15.0	27	33.3	35	51.4	0.007
Other wardsc	30	30.0	3	0.0	7	14.3	9	33.3	4	0.0	7	71.4	NDb
SPECIMEN TYPES
Blood	220	27.3	36	19.4	44	9.1	45	11.1	49	44.9	46	47.8	0.008
Ascitic fluid	130	18.5	24	4.2	22	4.5	35	22.9	18	16.7	31	35.5	0.005
Bronchoalveolar lavage fluid	36	33.3	4	0.0	13	23.1	10	40.0	4	50.0	5	60.0	NDb
Pus	29	24.1	6	33.3	6	0.0	3	0.0	5	20.0	9	44.4	NDb
Bile	27	14.8	6	0.0	5	0.0	10	20.0	1	0.0	5	40.0	NDb
Other specimensd	65	27.3	13	0.0	18	22.2	12	0.0	15	26.7	7	28.6	NDb
AGE (YEAR)
0–18	26	19.2	3	0.0	4	25.0	6	0.0	9	33.3	4	25.0	NDb
19–45	138	19.6	26	11.5	26	11.5	35	8.6	21	28.6	30	40.0	0.016
46–64	183	23.5	30	10.0	44	11.4	38	21.1	36	33.3	35	42.9	0.003
65 and above	160	26.3	30	13.3	34	8.8	36	22.2	26	42.3	34	47.1	0.004

^aStatistical analysis for fluconazole non-susceptible rate of CHIF-NET14 vs. CHIF-NET10

^bND, not done because of small sample size.

^cIncluding gynecology, pediatric, geriatric and dermatology wards.

^dIncluding pleural fluid, venous catheter, cerebrospinal fluid, tissue and peritoneal dialysate fluid.