Figure 5.

Two simulated images are shown on the third row where the image on the left is resampled from the input baseline image I_b, and the image on the right is resampled from another image I_r of the same subject. Both I_b and I_r had already been corrected for the bias field intensity inhomogeneity. The intensity histograms shown are of a selected ROI (shown on the last row) where there is no significant morphological changes between the images. From the histograms we can see that the simulated image I_{s2, t1} has a different intensity characteristics than I_b, while the simulated image I_{s1, t1} has intensity characteristics that closely matches to that of I_b.