Table 3.
Comparison of diagnostic accuracy between the MC-ASRS and SRS scales in screening for autism spectrum disorder in children aged 6–12 years.
| MC-ASRS | SRS | |
|---|---|---|
| True positives | 172 | 179 |
| False negatives | 13 | 6 |
| False positives | 268 | 284 |
| True negatives | 1325 | 1309 |
| Sensitivity (95% CI) | 93.0% (88.3–96.2) | 96.8% (93.1–98.8) |
| Specificity (95% CI) | 83.2% (81.2–85.1) | 82.2% (80.2–84.0) |
| Positive likelihood ratio (95% CI) |
553% (492–621) | 543% (487–605) |
| Negative likelihood ratio (95% CI) |
8.45%(5.0–14.3) | 3.95% (1.8–8.7) |
| Odds ratio (95% CI) | 65.4(36.9–116.0) | 138.0 (61.6–307.0) |
| Positive predictive value (95% CI) |
39.1% (34.5–43.8) | 38.7% (34.2–43.3) |
| Negative predictive value (95% CI) |
99.0% (98.3–99.5) | 99.5% (99.0–99.8) |
| False-positive rate, % | 16.8% | 17.8% |
MC-ASRS Modified Chinese Autism Spectrum Rating Scales, SRS Social Responsiveness Scale, 95% CI 95% confidence interval.