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A 45-year-old smoking man diagnosed with desquamative interstitial pneumonia (DIP) by a) cryo-transbronchial lung biopsy (haematoxylin–eosin stain) showing b) thick alveolar septa filled by numerous macrophages with c) CD68 staining. A 67-year-old man diagnosed with silicosis by d) cryo-transbronchial lung biopsy showing e) a silicotic nodule (black arrow) and f) silica crystals with polarised light (white arrow).
