Table 2.
Changes in cardiovascular autonomic reflex tests during the study in patients who received quinapril (group A) and in those who did not (group B).
| Group A (n = 31) | Group B (n = 32) | p (group A versus group B at end of treatment) | |||||
|---|---|---|---|---|---|---|---|
| Baseline | End of treatment |
p (versus baseline) |
Baseline | End of treatment |
p (versus baseline) |
||
| E/I index | 1.11 ± 0.06 | 1.23 ± 0.12 | 0.011 | 1.09 ± 0.06 | 1.04 ± 0.04 | 0.007 | <0.001 |
| MCR | 18.1 ± 6.2 | 38.7 ± 20.5 | 0.006 | 14.2 ± 4.2 | 8.1 ± 4.5 | 0.01 | <0.001 |
| SD | 31.1 ± 11.9 | 56.6 ± 23.0 | 0.004 | 28.2 ± 9.9 | 15.5 ± 7.4 | <0.05 | <0.001 |
| Valsalva index | 1.48 ± 0.28 | 1.56 ± 0.33 | NS | 1.52 ± 0.22 | 1.50 ± 0.28 | NS | NS |
| 30 : 15 index | 1.15 ± 0.12 | 1.18 ± 0.12 | NS | 1.15 ± 0.06 | 1.08 ± 0.04 | <0.05 | <0.001 |
| OH | 16.0 ± 11.8 | 10.4 ± 6.1 | NS | 18.5 ± 4.5 | 28.0 ± 6.3 | 0.018 | <0.001 |
E/I: expiration/inspiration; MCR: mean circular resultant; SD: standard deviation; OH: orthostatic hypotension.