Table 5.
Neurocognitive functions of the patients with schizophrenia and distribution by genotypes of the three SNPs.
| Parameters | G82S | p value | -374T/A | p value | -429T/C | p value | |||
|---|---|---|---|---|---|---|---|---|---|
| GG | GS + SS | TT | TA + AA | TT | TC + CC | ||||
| n = 121 | n = 84 | n = 159 | n = 46 | n = 185 | n = 20 | ||||
| BACS | |||||||||
| Digit sequencing task | 16.64 ± 9.30 | 14.93 ± 9.71 | 0.203 | 16.05 ± 9.70 | 15.57 ± 8.80 | 0.761 | 14.85 ± 8.95 | 16.06 ± 9.56 | 0.589 |
| Category instances | 30.73 ± 12.75 | 31.33 ± 12.56 | 0.737 | 30.59 ± 13.37 | 32.30 ± 9.73 | 0.339 | 26.30 ± 10.84 | 31.48 ± 12.75 | 0.082 |
| Controlled oral word association test | 9.86 ± 5.71 | 10.36 ± 6.50 | 0.563 | 10.01 ± 5.95 | 10.24 ± 6.39 | 0.823 | 7.60 ± 4.37 | 10.33 ± 6.14 | 0.054 |
| List learning | 22.06 ± 12.07 | 22.19 ± 13.67 | 0.942 | 21.62 ± 12.71 | 23.83 ± 12.73 | 0.300 | 22.55 ± 9.77 | 22.06 ± 13.02 | 0.872 |
| Token motor task | 44.91 ± 9.80 | 47.31 ± 14.24 | 0.182 | 46.03 ± 11.97 | 45.43 ± 11.54 | 0.767 | 47.05 ± 13.88 | 45.77 ± 11.65 | 0.647 |
| Tower of London | 7.70 ± 4.85 | 7.62 ± 4.86 | 0.934 | 7.47 ± 5.89 | 8.35 ± 5.18 | 0.438 | 5.70 ± 3.79 | 7.88 ± 4.80 | 0.169 |
| Symbol coding | 20.38 ± 12.52 | 21.17 ± 12.76 | 0.661 | 20.13 ± 12.70 | 22.67 ± 12.16 | 0.229 | 14.95 ± 9.49 | 21.32 ± 12.75 | 0.031 |
Values are the mean ± SD; BACS: Brief Assessment of Cognition in Schizophrenia.