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. 2017 Mar 8;2017:7809581. doi: 10.1155/2017/7809581

Figure 7.

Figure 7

Acarbose ameliorated EPC function and suppressed intracellular ROS levels via an Akt dependent pathway in vitro. Acarbose (1 μM) and p-Akt inhibitor and MK-2206 (1 μM) were added to the high glucose medium for 24 h. Measurement of tube formation (a), migration (b), and adhesion (c) capacity of BM-EPCs. Determination of intracellular NO level (d) and O2− level (e). ∗∗∗P < 0.001, ∗∗P < 0.01, and ∗P < 0.05. Values are expressed as the mean ± standard deviation ((a), (b), (c): n = 6 per group; (d), (e): n = 7 per group). Scale bar = 100 μm. Con, control; HG, high glucose; Aca, acarbose; MK, MK-2206.