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. 2017 Mar 8;2017:3671751. doi: 10.1155/2017/3671751

Figure 3.

Figure 3

Effects of MG132 on diabetes-induced renal fibrosis in wild-type mice (a) and Nrf2-KO mice (b) were determined by detecting the expression of FN and TGF-β with western blotting assay. Diabetes-induced fibrotic changes (fold) between wild-type and Nrf2-KO mice and the decreased percentages of these changes with MG132 between WT and Nrf2-KO diabetic mice were compared (c). Data are presented as mean ± SD. p < 0.05 versus WT/control or Nrf2-KO/control correspondingly; #p < 0.05 versus WT/DM or Nrf2-KO/DM correspondingly; &p < 0.05 versus WT mice.