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. 2017 Mar 8;2017:3671751. doi: 10.1155/2017/3671751

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Copyright © 2017 Lili Kong et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Effects of MG132 on diabetes-induced renal oxidative damage were determined by detecting the expression of 3-NT (a) and 4-HNE (b) with western blotting assay. Diabetes-induced changes of oxidative damage (fold) between wild-type and Nrf2-KO mice and the decreased percentages of these changes with MG132 between WT and Nrf2-KO diabetic mice were compared (c). Data are presented as mean ± SD. ^∗p < 0.05 versus WT/control or Nrf2-KO/control correspondingly; ^#p < 0.05 versus WT/DM or Nrf2-KO/DM correspondingly; ^&p < 0.05 versus WT mice.