Figure 1. Schematic organization of V. cholerae T6SS clusters.
Striped arrows denote genes encoding VgrG effectors; non-striped coloured arrows denote variable effector (large arrows) or immunity genes (small arrows); grey arrows indicate conserved genes based on cluster tags from the reference genome of V. cholerae N16961. Not pictured: VCA0122, the coding region of which is frequently interrupted by deletions. Boxed region denotes the EI module. Extended 3′-region is of variable length and gene content, and all coloured genes vary in length. Large cluster extends further upstream than shown in figure.