Table 1. Patient and tissue sample population by grade at the time of surgery, histological subtype, and IDH mutation status.
Grade/Hist | Total patients (samples) | IDH-wt (samples) | IDH-mut (samples) | IDH-uncertain (samples) |
---|---|---|---|---|
All | 126 (219) | 15 (26) | 108 (190) | 3 (3) |
II | 62 (103) | 10 (16) | 50 (85) | 2 (2) |
III | 50 (89) | 2 (4) | 47 (84) | 1 (1) |
IV | 14 (27) | 3 (6) | 11 (21) | — |
AS | 52 (83) | 8 (12) | 42 (69) | 2 (2) |
OA | 30 (57) | 5 (10) | 24 (46) | 1 (1) |
OD | 44 (79) | 2 (4) | 42 (75) | — |
The patient population comprised astrocytoma, oligodendroglioma, and oligoastrocytoma histological subtypes. The majority of patients (88%) harbored IDH-mutant lesions and 64 patients (51%) had undergone MP. It is of note that 10 of the patients were scanned at two distinct recurrences.