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. 2017 Mar 22;11:73. doi: 10.3389/fncel.2017.00073

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Copyright © 2017 Kandimalla, Dash, Kalita, Choudhury, Malampati, Devi, Ramanathan, Talukdar and Kotoky.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of different drug treatment on thermal hyperalgesia induced by hot plate method in diabetic neuropathic animals at different time intervals. All the results were expressed in mean ± S.D (n = 6). ^∧ is p ≤ 0.05 in comparison of 4th week with 0th week. ^* is p ≤ 0.05 in comparison of 6th and 8th week with 4th week. $ is p ≤ 0.05 in comparison with insulin alone treated diabetic group at corresponding weeks. ARBME, A. reticulata bark methanol extract; ARBWF, A. reticulata bark water fraction; ZJME, Z. jujuba root bark methanol extract; ZJWF, Z. jujuba root bark water fraction.