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. Author manuscript; available in PMC: 2017 Jun 5.
Published in final edited form as: Nature. 2016 Dec 5;541(7635):102–106. doi: 10.1038/nature20789

Figure 3. SFA-1 regulates metabolic effects of DR.

Figure 3

a, Heatmap of KEGG analysis in WT AL, DR and DR+sfa-1 RNAi at day 15. b, Venn diagram representing intron inclusion events at day 15 in AL, DR and DR+sfa-1 RNAi (#GO analysis in Supplementary Table 8). c, Maximal respiratory capacity (day 15 normalized to day 4, ** p<0.01, * p<0.05, unpaired, mean ± SEM, two-tailed t-test, n=100 animals/condition). d, Transcriptional induction of acs-2P::GFP in control and sfa-1 knockdown worms after 23 hours of fasting (representative image of 2 experiments shown).