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. Author manuscript; available in PMC: 2017 Mar 22.

Published in final edited form as: Bioorg Med Chem Lett. 2016 Mar 30;26(10):2481–2488. doi: 10.1016/j.bmcl.2016.03.102

Table 3.

Dopamine receptor selectivity of select compounds

Compound	D₄ (nM)	% inhibition at 10 µM^a

		D₁ (%)	D_2L (%)	D_2S (%)	D₃ (%)		D₅ (%)
4b	12.3			<50
4l	14.3	<50	78	76		<50
4n	10.4			<50
4p	11.6	<50	52	60		<50
4u	35			<50
4v	18.1			<50
4z	15.9	<50	64	64		<50
4aa	2.2	<50	94	93	70		<50
4dd	5.4	<50	87	82	70		<50
4ee	5.2	<50	78	76		<50
5k	10.4	<50	83	79	51		<50
5l	13.1	<50	88	82	76		<50
5m	10.8			<50
5n	10.1			<50
5u	21			<50
5y	3.3			<50
5aa	9.4			<50
5bb	7.4			<50

^a

% inhibition values were run in duplicate in a radioligand binding assay at EuroFins (www.EuroFins.com).