Figure 2.

Typical cystometrogram patterns of bladder activity during urodynamics at 2 and 4 weeks after SCI.

Normal bladder in sham group shows stable intravesical pressure without non-voiding contractions. SCI-induced hyperreflexic-bladder shows many large non-voiding contractions (more than 11 mmHg) during saline infusion. At 4 weeks, the micturition interval was more regular than at 2 weeks. After TIIA administration, bladder shows stable intravesical pressure without non-voiding contractions at 2 and 4 weeks after SCI. After MP administration, bladder shows some non-voiding contractions during saline infusion at 2 weeks after SCI, but clearly improved at 4 weeks. SCI: Spinal cord injury; TIIA: tanshinone IIA; MP: methylprednisolone.