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Comparison of the conventional coiled-coil tether USO1/p115 with the unconventional autophagic tether Atg17. The flexible coiled-coil dimer of USO1/p115 (left) tethers COPI-vesicles to the Golgi and spans a distance of ∼45 nm. In contrast, the S-shaped Atg17 dimer (right) captures 2 Atg9 vesicles bringing them in close proximity. Structures were prepared using PyMol and pdb-files 2W3C (head domain of USO1/p115), 2ZTA (coiled coil of USO/p115) and 4HPQ (Atg17).
