Table 1. Summary of reported cases of primary pyogenic ventriculitis.

Age	Gender	Symptoms	Meningism	Location	Underlying medical condition	Causative Agent	Sample	CSF pleocytosis	Antibiotic Treatment (days)	Neurosurgical treatment	Outcome	Ref
81	F	Right hemiplegia, aphasia	No	Left lateral ventricle	Unknown	S. aureus	CSF	Not performed	OXacillin (3), chloramphenicol (3)	No	Died	13
							Bloodculture not performed
39	M	Fatigue, fever, rigors, frontal headache, nuchal rigidity, facial paresis, right extensor plantar response	Yes	Left lateral ventricle	Multiple dental extractions	E. faecalis, E. coli, Peptostreptococcus spp.	Bloodculture	Yes	Not documented	Ventricle drainage	Survived	4
						Peptostreptococcus spp.	CSF
63	M	Headaches, feeling intermittently hot and sweaty, clumsiness, unsteadiness, diarrhoea and fever.	No	Right lateral ventricle	–	S. intermedius	CSF, 16s PCR	Yes	Cefotaxime (42), metronidazol (42)	EVD, later VP drain	Survived	14
							Bloodcultures negative		Rifampicin (14)
62	M	Fever + headache after trip to Japan	No	Right lateral ventricle	Gastric cancer, total gastrectomy	L. monocytogenes	CSF	Yes	Vancomycin (8), ceftriaxone (8), ampicillin (?), gentamicin (?)	EVD	Survived	15
							Bloodculture negative
66	M	Fever, anxiousness, restlessness, psychomotor retardation, generalized weakness and Suction-like mouth dyskinesias	No	Lateral ventricles	Laparoscopic left hemicolectomy, bowel obstruction and sclerosing peritonitis, renal failure	Methicillin Resistant S. aureus	Bloodculture, CSF	Yes	Vancomycin (5) followed by linezolid (49)	No	Survived	16
55	M	Fever, Intermittent occipital headache and right ankle swelling	No	Lateral ventricles	Hypertension, Hypercholesterolaemia, alcohol abuse and ex smoker (40 pack years)	N. meningitidis	Bloodculture	LP not performed due to raised INR	Piperacillin/tazobactam (1) and Clarithromycin (2) followed by ceftriaxone (41) and rifampicin (9)	No	Survived	Our case