Table 1.
Baseline characteristics of patients with infratentorial or cervical spinal cord demyelinating lesions in comparison to healthy control subjects
| Baseline characteristics | Patients (N = 23) |
Healthy controls (N = 12) |
P value |
|---|---|---|---|
| Sex, N(%) | |||
| Male | 6 (26%) | 8 (67%) | 0.31a |
| Female | 17 (74%) | 4 (33%) | |
| Age (years) | |||
| Mean (SD) | 44.8 (14.6) | 37.4 (14.5) | 0.87b |
| Range | 22 – 74 | 22 – 62 | |
| Ethnicity, N(%) | |||
| White | 22 (96%) | 11 (92%) | 0.57a |
| African American | 1 (4%) | 0 (0%) | |
| Middle Eastern | 0 (0%) | 1 (8%) | |
| Handedness, N(%) | |||
| Right | 21 (91%) | 11 (92%) | 0.73a |
| Left | 2 (9%) | 1 (8%) | |
| Disease subtype, N(%) | |||
| CIS | 4 | ||
| RRMS | 17 | ||
| SPMS | 1 | ||
| PPMS | 1 | - | - |
| Age at onset of disease symptoms (years) | |||
| Mean (SD) | 36.5 (14.7) | - | - |
| Range | 16 – 68 | ||
| Disease duration from onset of symptoms (years) | |||
| Mean (SD) | 8.7 (9.1) | - | - |
| Range | 0 – 39 | ||
| Lesion location on MRI, Nc | |||
| Infra-tentorial | 20 | - | - |
| Brainstem | 15 | ||
| Cerebellum | 18 | ||
| Cervical spinal cord | 18 | ||
aTwo-sided Fisher’s exact test
bTwo sided t-test
cData reflect the presence of multi-focal lesions within the CNS