Table 1.

Radiolabeling Yields with ¹¹¹In for CHXA″- and DOTA-Conjugated PAN-622 Monoclonal Antibody

Conjugate	Radiolabeling yield, %
CHXA″-PAN-622, 2 molar ratio	11.7 ± 0.5
CHXA″-PAN-622, 10 molar ratio	17.0 ± 1.2
CHXA″-PAN-622, 20 molar ratio	61.1 ± 2.1
CHXA″-PAN-622, 50 molar ratio	3.0 ± 0.2
DOTA-PAN-622-MAL, 8 minutes	0.07 ± 0.01
DOTA-PAN-622-MAL, 15 minutes	0.07 ± 0.01
DOTA-PAN-622-MAL, 30 minutes	0.10 ± 0.02
DOTA-PAN-622-NHS, 10:1	0.05 ± 0.01
DOTA-PAN-622-NHS, 20:1	0.19 ± 0.02