Fig. 2.

 Sequence for the conventional method (CM) of colorectal endoscopic submucosal dissection ¹⁵. First, 0.4 % sodium hyaluronate solution is injected into the submucosal layer under the lesion and the surrounding normal mucosa. a An initial mucosal incision is made for at least one-quarter of the circumference and approximately 5 mm from the distal side. b Submucosal dissection is performed by sliding the knife from the center toward the side. c Making an additional mucosal incision in a step-by-step manner toward the proximal side. d Dissection of the incised area in the same manner. e Incision and dissection of the remaining area. f Completion of the en bloc resection.