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. Author manuscript; available in PMC: 2017 Mar 22.
Published in final edited form as: Anal Chem. 2016 Sep 27;88(20):10301–10308. doi: 10.1021/acs.analchem.6b03148

Figure 3. Three MSn acquisition methods utilized for analyzing TMT-labeled, DSSO cross-linked peptides.

Figure 3

(A) Method 1: targeted identification method, ID-MS3. (B) Method 2: MultiNotch quantitation using synchronous precursor selection (SPS), SPS-MS3. (C) Method 3: combined acquisition method consisting of ID-MS3 with SPS-MS3, ID-SPS-MS3.