Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 24;22(2):194. doi: 10.3390/molecules22020194

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

p62 inhibition reduces Nrf2 target gene expression: (A) immunoblot analysis of p62 and GAPDH in HaCaT cells stably infected with a lentiviral vector expressing shRNA targeting p62 (shp62) or a negative shRNA control (shCon); and (B–G) real-time PCR analysis of the mRNA levels of: NQO1 (B); GCLC (C); HO-1 (D); Bcl-2 (E); Bcl-XL (F); and IL-8 (G) in cells as in (A). The cells were treated with or without arsenic (8 μM) over a time course. * p < 0.05, Student’s t-test, statistically significant between comparison groups.