Table 1.

Sequential clinical findings. Western immunoblot (WB), PCR, Bartonella alpha Proteobacteria growth medium (BAPGM) blood culture/PCR/DNA sequencing results and post-treatment Western blot antibody titration titers for three febrile Bartonella henselae-infected kittens

	Date	Clinical findings	Bartonella WB and titration titers	Blood PCR	BAPGM culture PCR
Case 1	3 September 2012	Temperature 39.8°C, lethargy	Negative	Negative	Negative
	5 September 2012			Negative	Negative
	7 September 2012			Negative	Negative
	11 October 2012	Temperature 40.8°C, lethargy	Negative	Bh *	Bh *
		Azithromycin 10 mg/kg for 21 days		Bh *
	12 November 2012		1:256,000
	12 May 2013	Titration testing	1:16,000 (16-fold decrease)
	28 August 2014	Follow-up testing	ND	Negative	Bh †
	30 August 2014		ND	Negative	Negative
	1 September 2014		1:16,000 (no change)	Negative	Negative
Case 2	21 August 2012	Presurgery	1:512,000
	3 September 2012	40.0°C, lethargy	ND	Bh*	Bh*
	5 September 2012		ND	Bh*	Bh*
	7 September 2012	Azithromycin 10 mg/kg for 21 days	ND	Bh*	Bh*
	2 March 2013	39.8°C, lethargy anorexia	1:512,000	Bh*	Bh*
		Pradofloxacin 7.5 mg/kg x 21 days	(no change)	Bh*
	5 September 2013	Titration testing	1:64,000 (eight-fold decrease)
	30 May 2014	Killed by dogs and lost to follow-up
Case 3	23 August 2012	37.7°C, lethargy anorexia neutropenia Azithromycin 10 mg/kg for 21 days	1:64,000	Bh*	Bh*
	7 May 2013	Titration testing	1:8,000 (eight-fold decrease)
	28 August 2014	Follow-up BAPGM triple blood draw and titration testing	ND	Bh*	Bh*
	30 August 2014		ND	Bh*	Bh*
	1 September 2014		1:32,000 (four-fold decrease)	Negative	Bh*

^*Bartonella henselae Houston-1 strain type based upon 16S-23S intergenic spacer DNA sequences

^†Bartonella henselae San Antonio-2 strain type based upon 16S-23S intergenic spacer DNA sequences

ND = not determined