Table 3. Inflammatory factors associated to OCT and UWFA findings of DME.
OCT and UWFA finding | p-value | ||
---|---|---|---|
DRT (n = 22) | no DRT (n = 36) | ||
IL-6 (ρg/ml) | 6.57 (17.60) | 1.09 (0.69) | 0.044 |
0.9 [0.9; 1.76] | 0.9 [0.9; 0.9] | ||
0.9 to 81.14 | 0.9 to 4.53 | ||
CME (n = 38) | no CME (n = 20) | ||
IL-10 (ρg/ml) | 1.29 (1.17) | 2.28 (3.33) | 0.012 |
1.1 [1.1; 1.1] | 1.1 [1.1; 1.32] | ||
1.1 to 8.21 | 1.1 to 12.12 | ||
enlarged FAZ (n = 6) | physiological FAZ (n = 36) | ||
IL-8 (ρg/ml) | 30.17 (38.69) | 9.64 (6.18) | 0.031 |
15.49 [10.73; 25.10] | 9.05 [5.02; 12.01] | ||
6.17 to 108.03 | 0.82 to 30.33 | ||
VEGF (ρg/ml) | 794.54 (1227.54) | 158.55 (239.81) | 0.031 |
374.07 [152.32; 571.07] | 26.3 [26.3; 211.52] | ||
26.3 to 3269.42 | 26.3 to 925.66 |
Variables are described (above to lower) by mean and standard deviation, median and interquartilic range [percentiles 25th, 75th], and absolute range.
Abbreviations: CME, cystoid macular edema; DRT, diffuse retinal thickening; DME, diabetic macular edema; FAZ, foveal avascular zone; n, number of cases; OCT, optical coherence tomography; UWFA, ultra-widefield fluorescein angiography.