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. 2017 Mar 22;12(3):e0173683. doi: 10.1371/journal.pone.0173683

Table 4. Drug consumption before inclusion (6 months) and after inclusion (from M1 to M3 and from M4 to M6).

Drugs NSAIDs (n = 199) IA HA (n = 202)
M-6 to M0 M1 to M3 M4 to M6 M-6 to M0 M1 to M3 M4 to M6
Arthrum H 2%
 Number of patients 0 (0%) 0 (0%) 0 (0%) 0 202(100%) 0 (0%)
 Mean number of boxes per patient treated 0 0 0 0 1 0
Mean cost per patient €0 €0 €0 €0 €30 €0
NSAIDs
 Number of patients 199 (100%) 199 (100%) 199 (100%) 202 (100%) 133 (66%) 89 (44%)
 Mean number of boxes per patient treated 14.4 7.3 7.9 12.1 6.4 6.7
Mean cost per patient €45.36 €20.84 €22.48 €38.18 €11.96 €8.39
Antalgics
 Number of patients 90 (45%) 94 (47%) 90 (45%) 145 (72%) 123 (61%) 105 (52%)
 Mean number of boxes per patient treated 7.2 3.3 3.5 11.4 3.9 3.1
Mean cost per patient €9.92 €4.53 €4.94 €15.71 €5.37 €4.26
Corticosteroids
 Number of patients 42 (21%) 56 (28%) 58 (29%) 46 (23%) 38 (19%) 18 (9%)
 Mean number of boxes per patient treated 6.6 3.2 3.0 6.3 3.0 3.1
Mean cost per patient €6.26 €3.11 €3.07 €6.18 €3.05 €3.09
Symptomatic slow action drugs (SYSADOA)
 Number of patients 74 (37%) 72 (36%) 72 (36%) 79 (39%) 69 (34%) 69 (30%)
 Mean number of boxes per patient treated 6.7 3.2 3.2 6.9 3.1 3.0
Mean cost per patient €27.9 €13.6 €13.9 €28.6 €14.9 €13.7
Proton pump inhibitors (PPI)
 Number of patients 50 (25%) 62 (31%) 58 (29%) 42 (21%) 30 (15%) 12 (6%)
 Mean number of boxes per patient treated 13.4 6.6 6.9 6.0 3.3 3.0
Mean cost per patient €6.9 €5.6 €6.1 €5.1 €3.9 €2.9
Total for drug treatments
Mean cost per patient €96.34 €47.68 €50.49 €93.77 €69.18 €32.34