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. 2017 Mar 10;12:462–468. doi: 10.1016/j.redox.2017.03.002

Scheme 1.

Scheme 1

GFP chromophore maturation and proposed mechanism for the catalytical consumption of NAD(P)H and generation of O2•–/H2O2 by GFP immature intermediates. The GFP chromophore maturation process is shown in black (adapted from Barondeau et al. [28]). Shown in red, the proposed reaction of the last immature intermediate of GFP with NAD(P)H leads to the catalytical generation of O2•–/H2O2 and consumption of NAD(P)H. The eGFP structure is shown (PDB# 2y0g).