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. 2017 Mar 22;12(3):e0174143. doi: 10.1371/journal.pone.0174143

Fig 4. Effects of GnRH-mediated olfacto-visual sensory integration on animal sexuality.

Fig 4

(A) Lateral view of transgenic zebrafish (GnRH::3-GFP; anterior to the left) that shows the TNs and TN axons in the brain (revealed by the expression of the GFP). Scale bar, 50 μm. (B) A cartoon showing the projection of TN axons (red) and the projection of RGC axons (green) to the hypothalamus. (C) GnRH signaling in the eye. Upon entering the retina, the TN axons synapse with DA-IPCs and RGCs. Most of the RGCs project axons to the visual cortex, but some of the RGCs project axons to the hypothalamus. Abbreviations: F, forebrain; H, hypothalamus; M, midbrain; P, photo receptor cells; R, retina; DA-IPC, dopaminergic interplexiform cell; INL, inner nuclear layer; IPL, inner plexiform layer; OB, olfactory bulb; ON, optic nerve; OPL, outer plexiform layer; RGC, retinal ganglion cells; TN, terminalis neuron.