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. 2017 Mar 22;12(3):e0174137. doi: 10.1371/journal.pone.0174137

Fig 4. LC–MS/MS analysis of 5-, 8-, 11-, 12- and 15-HETE levels in WT and Tie2-CYP2J2 Tr mouse heart perfusates at baseline and post-ischemia.

Fig 4

In Tie2-CYP2J2 Tr mice, the levels of 8-HETE (B) and 12-HETE (D) were increased compared to WT mice at baseline and post-ischemia (P < 0.05). In both WT and Tie2-CYP2J2 Tr mice, post-ischemic levels of 5-HETE (A), 8-HETE (B), 11-HETE (C), 12-HETE (D) and 15-HETE (E) were decreased compared to baseline levels (P < 0.05). * P < 0.05 versus baseline WT. # P < 0.05 versus WT post-ischemia. Ф P < 0.05 versus baseline Tie2-CYP2J2 Tr. n = 12 per group.