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. 2017 Mar 22;12(3):e0173891. doi: 10.1371/journal.pone.0173891

Fig 1. Partial podocyte replacement in Ren1cCre /R26R-ConfettiTG/WT mice with experimental FSGS.

Fig 1

(A-C) Double staining was performed for the podocyte marker p57 (brown, nuclear) and counterstain with Periodic acid Schiff's (pink stains matrix, blue stains nuclei) in reporter mice at baseline (A), day 14 (D14) FSGS (B) and D28 FSGS (C). (D) Podocyte number was lower at D14 compared to baseline, and partial recovered by D28. (E) Glomerulosclerosis was highest at D14 FSGS, with a significant reduction by D28. (F) The urinary albumin to creatinine ratio (ACR) was significantly higher at D14 FSGS, with a significant decrease by D28 of FSGS.