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. 2017 Mar 22;12(3):e0174280. doi: 10.1371/journal.pone.0174280

Table 2. Adverse effects of UFUR group vs comparison group.

UFUR group Comparison group
No. of Patients (%) No. of Patients (%) p-value
Leukopenia
    Any 21 (18.6) 17(12.9) NS
    Grade 3 1(0.8) 0(0) NS
Neutropenia
    Any 19(16.8) 14(10.6) NS
    Grade 3 0(0) 0(0) NS
Thrombocytopenia
    Any 22(19.5) 18(13.6) NS
    Grade 3 1 (0.8) 1(0.8) NS
Anemia
    Any 29 (35.4) 36(27.3) NS
    Grade 3 13(11.5) 10(7.6) NS
Anorexia
    Any 30 (26.5) 14(10.6) 0.01
    Grade 3 0(0) 0(0) NS
Diarrhea
    Any 15(13.2) 10(7.6) NS
    Grade 3 0 (0) 0(0) NS
Mucositis
    Any 17 (15.0) 14(10.6) NS
    Grade 3 0(0) 0(0) NS
Nausea/vomiting
    Any 20(17.6) 12(9.1) NS
    Grade 3 0(0) 0(0) NS

There is no grade 4 or 5 toxicity.