Table 2. Clinical outcomes.
| Outcome | Admission serum chloride level (mmol/L) | ||||||
|---|---|---|---|---|---|---|---|
| <95 | 95–100 | 100–105 | 105–108 | 108–113 | 113–118 | >118 | |
| Hospital mortality | 127 (3.8) | 226 (2.2) | 355 (1.1) | 164 (0.9) | 164 (1.7) | 53 (3.6) | 24 (9.6) |
| Mortality, OR (95%CI) | |||||||
| Model 1: unadjusted | 4.29 (3.39–5.42) | 2.46 (2.01–3.02) | 1.16 (0.97–1.40) | 1 (ref) | 1.89 (1.52–2.35) | 4.03 (2.91–5.47) | 11.64 (7.27–17.89) |
| Model 2# | 2.63 (2.06–3.34) | 1.66 (1.35–2.05) | 1.11 (0.92–1.35) | 1 (ref) | 1.61 (1.29–2.01) | 2.96 (2.12–4.05) | 6.34 (3.84–10.09) |
| Model 3: Model 2 and Na | 2.14 (1.59–2.87) | 1.51 (1.21–1.89) | 1.08 (0.89–1.30) | 1 (ref) | 1.65 (1.32–2.06) | 3.14 (2.25–4.32) | 7.26 (4.35–11.67) |
| Hospital LOS | 5 (3–9) | 5 (3–8) | 4 (3–6) | 4 (3–7) | 5 (3–7) | 6 (5–9) | 6 (4–12) |
| LOS, relative prolongation (95% CI) |
|||||||
| Model 1: unadjusted | 1.28 (1.25–1.32) | 1.13 (1.11–1.15) | 0.98 (0.97–0.99) | 1 (ref) | 1.15 (1.13–1.17) | 1.45 (1.40–1.50) | 1.53 (1.40–1.67) |
| Model 2# | 1.25 (1.22–1.29) | 1.11 (1.09–1.12) | 0.98 (0.97–1.002) | 1 (ref) | 1.13 (1.11–1.15) | 1.39 (1.34–1.45) | 1.45 (1.33–1.58) |
| Model 3: Model 2 and Na | 1.29 (1.26–1.34) | 1.12 (1.10–1.14) | 0.99 (0.97–1.01) | 1 (ref) | 1.12 (1.10–1.14) | 1.39 (1.33–1.43) | 1.42 (1.31–1.55) |
| Hospital survivor (n = 75,606) | 3,233 | 10,025 | 33,292 | 17,902 | 9,492 | 1,437 | 225 |
| Discharge disposition | |||||||
| - Home | 2,203 (68) | 7,398 (74) | 27,123 (81) | 14,590 (81) | 7,558 (80) | 1,072 (75) | 139 (62) |
| - Home Health Care | 305 (9) | 856 (9) | 1,897 (6) | 994 (6) | 568 (6) | 96 (7) | 12 (5) |
| - In-hospital rehab+ | 13 (0.4) | 45 (0.4) | 91 (0.3) | 75 (0.4) | 36 (0.4) | 12 (0.9) | 1 (0.4) |
| - Skilled Nursing facility + | 686 (21) | 1,680 (17) | 4,066 (12) | 2,191 (12) | 1,299 (14) | 247 (17) | 69 (31) |
| - Swing bed+ | 26 (0.8) | 46 (0.4) | 115 (0.3) | 52 (0.3) | 31 (0.3) | 10 (0.7) | 4 (2) |
| Discharge to short or long term care facility, OR (95% CI) | |||||||
| Model 1: unadjusted | 1.94 (1.77–2.13) | 1.44 (1.35–1.54) | 0.99 (0.94–1.04) | 1 (ref) | 1.13 (1.05–1.21) | 1.55 (1.34–1.78) | 3.29 (2.47–4.35) |
| Model 2# | 1.46 (1.31–1.62) | 1.16 (1.08–1.26) | 0.97 (0.92–1.03) | 1 (ref) | 1.16 (1.08–1.26) | 1.89 (1.61–2.20) | 3.53 (2.53–4.88) |
| Model 3: Model 2 and Na | 1.48 (1.30–1.69) | 1.18 (1.08–1.28) | 0.98 (0.92–1.04) | 1 (ref) | 1.16 (1.07–1.26) | 1.88 (1.60–2.19) | 3.49 (2.50–4.85) |
#model 2: Adjusted for age, sex, Charlson comorbidities score, eGFR and principal diagnosis.
+discharge to short or long term care facility