Table 2.
Pharmacogenomics clinical decision support interventions | Number of months in production |
Monthly ratesa |
---|---|---|
Abacavir - HLA-B*57:01 | ||
Drug Order Attempted, Total Popup Alerts | 3.7 | |
Drug order attempted, alerted patient has positive HLA-B*5701 | 0.9 | |
Drug order attempted, alerted patient should be tested for HLA-B*5701 | 30 | 2.8 |
Patient Tested, Result Positive, Physician Notified, Allergy Added | 0.3 | |
Carbamazepine - HLA-B*15:02 | ||
Drug Order Attempted, Total Popup Alerts | 1.3 | |
Drug order attempted, alerted patient has positive HLA-B*1502 | 27 | 0.1 |
Drug order attempted, alerted patient should be tested for HLA-B*1502 | 1.2 | |
Patient Tested, Result Positive, Physician Notified, Problem Added | 0.0 | |
Thiopurine - TPMT | ||
Drug Order Attempted, Total Popup Alerts | 77.6 | |
Drug order attempted, alerted patient has intermediate or low TPMT test results | 25 | 11.4 |
Drug order attempted, alerted to consider patient be tested for TPMT | 66.2 | |
Patient Tested, Result Positive, Physician Notified, Problem Added | 54.7 | |
Codeine/Tramadol/Tamoxifen - CYP2D6 | ||
Drug Order Attempted, Total PopUp Alerts | 15.0 | |
Drug order attempted, alerted patient at risk with Extensive to Ultra Rapid test result | 6.0 | |
Drug order attempted, alerted patient at risk with Ultra Rapid test result | 21 | 3.9 |
Drug order attempted, alerted patient at risk with Poor to Intermediate test result | 1.5 | |
Drug order attempted, alerted patient at risk with Poor test result | 3.6 | |
Drug order attempted, alerted patient at risk with Intermediate to Ultra Rapid test result | 0.0 | |
Patient Tested, Result At RISK, Physician Notified, Problem Added | 25.1 | |
Simvastatin - SLCO1B1 | ||
Drug Order Attempted, Total PopUp Alerts | 0.7 | |
Drug order attempted, alerted for TC Genotype | 14 | 0.7 |
Drug order attempted, alerted for CC Genotype | 0.0 | |
Patient Tested, Result At RISK, Physician Notified, Problem Added | 0.6 | |
Warfarin - CYP2C9/VKORC1 | ||
Drug Order Attempted, Total PopUp Alerts | 10 | 0.7 |
Drug order attempted, dosing algorithm recommendations presented for warfarin order | 0.7 | |
Drug order attempted, unable to display dosing algorithm due to missing data | 0.0 | |
Clopidogrel - CYP2C19 | ||
Drug Order Attempted, Total PopUp Alerts | 5.6 | |
Drug order attempted, alerted patient at risk with Intermediate test result | 4.6 | |
Drug order attempted, alerted patient at risk with Poor to Intermediate test result | 10 | 0.2 |
Drug order attempted, alerted patient at risk with Poor test result | 0.8 | |
Patient Tested, Result At RISK, Physician Notified, Problem Added | 28.2 | |
Allopurinol - HLA-B*58:01 | ||
Drug Order Attempted, Total PopUp Alerts | 4.7 | |
Drug order attempted, alerted patient at risk with Positive result | 6 | 0.0 |
Drug order attempted, alerted patient should be tested for HLA-B*5801 | 4.7 | |
Patient Tested, Result At RISK, Physician Notified, Problem Added | 0.0 |
Monthly rate of events calculated as same provider, same patient, same drug order within 24 hours.