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. Author manuscript; available in PMC: 2017 Jun 15.
Published in final edited form as: Biometrics. 2016 Sep 22;73(2):656–665. doi: 10.1111/biom.12589

Table 2.

Region X 2011 chlamydia and gonorrhea data. Average number of tests (sample standard deviation, SD) from B = 5000 sets of pools for 2-, 3-, and 4-stage hierarchical algorithms. The optimal configuration is determined by minimizing n1-1E(T(S)) using the 2010 prevalences; see Web Appendix E. The percent reduction in the average number of tests is also shown. The maximum allowable master pool size is 20.

State # Stages Swab
Urine
Configuration # Tests (SD) % Reduction Configuration # Tests (SD) % Reduction
Alaska S = 2 5 : 1 1509.9 (30.7) – – 4 : 1 2615.6 (31.5) – –
S = 3 9 : 3 : 1 1343.7 (31.2) 11.0 9 : 3 : 1 2460.4 (42.1) 5.9
S = 4 18 : 6 : 3 : 1 1352.4 (38.5) 10.4 18 : 6 : 3 : 1 2512.0 (54.1) 4.0

Idaho S = 2 5 : 1 3938.0 (49.9) – – 5 : 1 2253.4 (34.8) – –
S = 3 9 : 3 : 1 3511.3 (51.1) 10.8 9 : 3 : 1 2047.1 (37.4) 9.2
S = 4 18 : 6 : 3 : 1 3516.0 (66.0) 10.7 18 : 6 : 3 : 1 2082.2 (48.5) 7.6

Oregon S = 2 5 : 1 19633.1 (108.9) – – 4 : 1 4459.0 (39.2) – –
S = 3 9 : 3 : 1 17322.5 (112.1) 11.8 9 : 3 : 1 4073.1 (52.7) 8.7
S = 4 18 : 6 : 3 : 1 17272.5 (140.2) 12.0 18 : 6 : 3 : 1 4134.2 (68.3) 7.3

Washington S = 2 5 : 1 10497.1 (80.4) – – 5 : 1 8324.5 (66.2) – –
S = 3 9 : 3 : 1 9199.5 (81.0) 12.4 9 : 3 : 1 7454.5 (70.2) 10.5
S = 4 18 : 6 : 3 : 1 9162.6 (103.8) 12.7 18 : 6 : 3 : 1 7521.1 (90.1) 9.7