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a–f. Cell invasion in shMSI2-1 (b) and shMSI2-2 (c) transfected BxPC-3 was significantly decreased, compared with that in corresponding scramble group (a). However, Numb knockdown can significantly reverse the decrease of cell invasion in shMSI2-1 (d) and shMSI2-2 (e) transfected BxPC-3 cells. Bars indicate ± S.E.*, P <0.05; **, P <0.01 compared with the control.
