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. 2016 Apr 15;8(9):14359–14373. doi: 10.18632/oncotarget.8736

Table 2. Association of MSI2 and Numb expressions with clinical data.

Parameters No. of patients MSI2 P Numb P
low high Negative Positive
Cases 75 28 47 40 35
Age(years)
 ≤65 55 21 34 0.801 29 26 0.861
 >65 20 7 13 11 9
Gender
 Male 52 21 31 0.411 30 22 0.255
 Female 23 7 16 10 13
Tumor location
 Head 54 21 33 0.655 28 26 0.680
 Body-tail 21 7 14 12 9
Tumor size(cm)
 <2.5 25 15 10 0.004 8 17 0.009
 ≥2.5 50 13 37 32 18
Differentiation
 Well 27 13 14 0.146 8 19 0.002
Moderate and poor 48 15 33 32 16
 T stage
 T1+T2 21 11 10 0.093 9 12 0.257
 T3+T4 54 17 37 31 23
Lymph nodes metastasis
 N0(negative) 55 23 32 0.183 26 29 0.081
 N1(positive) 20 5 15 14 6
 UICC stage
 I+IIA 51 23 28 0.043 22 29 0.010
 IIB+III 24 5 19 18 6
Perineural invasion
 Absent 61 25 36 0.172 31 30 0.362
 Present 14 3 11 9 5
Vascular permeation
 Absent 42 18 24 0.265 20 22 0.263
 Present 33 10 23 20 13
Pre-therapeutic CA19-9 level
 <37 U/ml 23 10 13 0.464 9 14 0.101
 ≥37 U/ml 52 18 34 31 21
Postoperative Liver metastasis
 Negative 48 20 28 0.301 24 24 0.440
 Positive 27 8 19 16 11