Table 2. Association of MSI2 and Numb expressions with clinical data.
Parameters | No. of patients | MSI2 | P | Numb | P | ||
---|---|---|---|---|---|---|---|
low | high | Negative | Positive | ||||
Cases | 75 | 28 | 47 | 40 | 35 | ||
Age(years) | |||||||
≤65 | 55 | 21 | 34 | 0.801 | 29 | 26 | 0.861 |
>65 | 20 | 7 | 13 | 11 | 9 | ||
Gender | |||||||
Male | 52 | 21 | 31 | 0.411 | 30 | 22 | 0.255 |
Female | 23 | 7 | 16 | 10 | 13 | ||
Tumor location | |||||||
Head | 54 | 21 | 33 | 0.655 | 28 | 26 | 0.680 |
Body-tail | 21 | 7 | 14 | 12 | 9 | ||
Tumor size(cm) | |||||||
<2.5 | 25 | 15 | 10 | 0.004 | 8 | 17 | 0.009 |
≥2.5 | 50 | 13 | 37 | 32 | 18 | ||
Differentiation | |||||||
Well | 27 | 13 | 14 | 0.146 | 8 | 19 | 0.002 |
Moderate and poor | 48 | 15 | 33 | 32 | 16 | ||
T stage | |||||||
T1+T2 | 21 | 11 | 10 | 0.093 | 9 | 12 | 0.257 |
T3+T4 | 54 | 17 | 37 | 31 | 23 | ||
Lymph nodes metastasis | |||||||
N0(negative) | 55 | 23 | 32 | 0.183 | 26 | 29 | 0.081 |
N1(positive) | 20 | 5 | 15 | 14 | 6 | ||
UICC stage | |||||||
I+IIA | 51 | 23 | 28 | 0.043 | 22 | 29 | 0.010 |
IIB+III | 24 | 5 | 19 | 18 | 6 | ||
Perineural invasion | |||||||
Absent | 61 | 25 | 36 | 0.172 | 31 | 30 | 0.362 |
Present | 14 | 3 | 11 | 9 | 5 | ||
Vascular permeation | |||||||
Absent | 42 | 18 | 24 | 0.265 | 20 | 22 | 0.263 |
Present | 33 | 10 | 23 | 20 | 13 | ||
Pre-therapeutic CA19-9 level | |||||||
<37 U/ml | 23 | 10 | 13 | 0.464 | 9 | 14 | 0.101 |
≥37 U/ml | 52 | 18 | 34 | 31 | 21 | ||
Postoperative Liver metastasis | |||||||
Negative | 48 | 20 | 28 | 0.301 | 24 | 24 | 0.440 |
Positive | 27 | 8 | 19 | 16 | 11 |