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. 2017 Jan 12;8(9):14374–14394. doi: 10.18632/oncotarget.14605

Figure 9. Alterations in Cellular Metabolism in Response to Low Glucose Conditions and Loss in Androgen Sensititivity.

Figure 9

A number of proteins identified and included as ‘signatures’ for low glucose (LG) conditions or androgen sensitivity (AI v AS) have known roles in regulation of the glycolysis pathway A. and TCA cycle B. As indicated in figure 9, a number of key enzymes within both pathways are either up or down-regulated in response to low glucose treatment (LG treatment) or between androgen independent (AI) and androgen sensitive (AS) PCa cell lines.