Table 5. Prosate Cancer Databases for external validation of selected proteins.
Database | Samples | Clinical Data | Details | Matching Genes (LG) | CI (LG) | Survival ROC (LG) | Matching Genes (AS) | CI (AS) | Survival ROC (AS) |
Taylor MSKCC Prostate | 140 | Recurrence, Gleason, Stage | Concordant assessment of DNA copy number, mRNA expression, and focused exon resequencing in 218 prostate cancer tumors | 31/31 | 82.27 | 0.85 | 36/36 | 83.17 | 0.82 |
Galsky Oh - Prostate - GSE45705 | 61 | Survival | qPCR profiling of whole blood from patients with castration-resistant prostate cancer | 2/31 | 52.92 | 0.44 | 1/36 | 53.86 | 0.65 |
Sboner Rubin Prostate GSE16560 | 281 | Gleason | cDNA-mediated gene expression profiling on formalin-fixed paraffin-embedded transurethral resection of prostate (TURP) samples | 22/31 | 67.49 | 0.78 | 31/36 | 63.39 | 0.67 |
Gulzar-Prostate-GSE40272 | 98 | Recurrence | Gene-expression profiling of prostate tumors | 31/31 | 80.90 | 0.93 | 36/36 | 79.34 | 0.82 |
Kollmeyer-Jenkins Prostate GSE10645-GPL5858 | 596 | Survival, Age, PSA, Stage, Grade | Gene expression microarray of tumors using RNA from archival FFPE tissue | 2/31 | 55.89 | 7/36 | 69.92 | 0.76 | |
PRAD - TCGA - Prostate adenocarcinoma June 2016 | 497 | Survival | Gene-expression profiling of prostate tumors | 31/31 | 95.08 | 0.87 | 36/36 | 95.65 | 0.88 |
LG = Low Glucose; CI = Concordance index; ROC = Receiver operating characteristic; AS = Androgen Sensitivity