Table 1. Aberrations in six candidate driver genes.
Gene | Cancer | Aberration | # Analyzed Tumors | % Tumors with Aberration |
---|---|---|---|---|
RPL5 | SKCM | mutations | 279 | 2.5 |
deletions | 293 | 25.3 | ||
GBM | mutations | 283 | 2.5 | |
deletions | 560 | 8.4 | ||
BRCA | mutations | 976 | 0.2 | |
deletions | 1016 | 33.9 | ||
RPL11 | SKCM | mutations | 279 | 1.4 |
RPL23A | UCEC | mutations | 248 | 2.0 |
amplifications | 515 | 12.6 | ||
RPS5 | STAD | mutations | 221 | 1.4 |
RPS20 | UCEC | mutations | 248 | 1.2 |
RPSA | STAD | mutations | 221 | 2.7 |