Table 1. Association between miR-27a and clinical characteristics in 50 patients with LSCC.
| Features | No. of cases | miR-27aexpression (mean ± SEM) | P-value |
|---|---|---|---|
| Age | |||
| < 60 | 22 | 4.964 ± 0.939 | 0.1607 |
| ≥ 60 | 28 | 3.431 ± 0.606 | |
| Gender | |||
| male | 42 | 4.074 ± 0.581 | 0.8944 |
| female | 8 | 4.272 ± 1.540 | |
| Smoking | |||
| smoker | 40 | 4.100 ± 0.593 | 0.9835 |
| nonsmoker | 10 | 4.128 ± 1.358 | |
| Drinking | |||
| drinker | 36 | 4.340 ± 0.967 | 0.7895 |
| nondrinker | 14 | 4.014 ± 0.656 | |
| Differentiation | |||
| well | 16 | 8.016 ± 1.790 | 0.0002*** |
| moderate | 24 | 3.843 ± 0.560 | |
| poor | 10 | 2.136 ± 0.336 | |
| Lymph node | |||
| negative | 31 | 2.859 ± 0.491 | 0.0023** |
| positive | 19 | 6.139 ± 1.030 | |
| Clinical stage | |||
| I | 7 | 2.155 ± 0.346 | 0.0006*** |
| II | 15 | 2.805 ± 0.827 | |
| III | 23 | 4.282 ± 0.689 | |
| IV | 5 | 9.928 ± 2.263 |
Notes: One-way ANOVOA was used to analyze the correlation between the miR-27a expression and clinical features of each patient. ** and *** indicates P < 0.01 and P < 0.001, respectively.