Table 5. Pearson correlation of MAGE expression with known prognostic markers.
T | N | M | ECE | L | V | Grading | R | HPV-DNA | HPV-DNA, p16 | Sex | Primary Site | Smoking | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
pan-MAGE (M3H67) | Correlation Coefficient | 0.148 | 0.112 | (-)0.064 | 0.047 | 0.102 | 0.069 | 0.062 | 0.02 | (-)0.115 | (-)0.172 | (-)0.02 | 0.07 | 0.158 |
p-value | 0.002** | 0.023* | 0.188 | 0.547 | 0.207 | 0.408 | 0.251 | 0.73 | 0.018* | <0.001*** | 0.674 | 0.152 | 0.004** | |
number of cases | 420 | 415 | 423 | 167 | 155 | 147 | 346 | 311 | 424 | 420 | 424 | 424 | 326 | |
MAGE-A3/A4 (57B) | Correlation Coefficient | 0.107 | 0.074 | (-)0.032 | (-)0.004 | 0.1 | 0.106 | 0.065 | 0.049 | (-)0.14 | (-)0.146 | (-)0.012 | 0.082 | 0.113 |
p-value | 0.029* | 0.131 | 0.506 | 0.964 | 0.216 | 0,2 | 0.229 | 0.385 | 0.004** | 0.003** | 0.799 | 0.092 | 0.042* | |
number of cases | 420 | 415 | 423 | 167 | 155 | 147 | 346 | 312 | 424 | 420 | 424 | 424 | 326 | |
MAGE-A1 (MA454) | Correlation Coefficient | 0.168 | 0.148 | 0.034 | 0.027 | 0.079 | 0.078 | (-)0.001 | 0.08 | (-)0.079 | (-)0.096 | (-)0.06 | 0.089 | 0.035 |
p-value | 0.001** | 0.002** | 0.488 | 0.731 | 0.33 | 0.349 | 0.984 | 0.157 | 0.105 | 0.049* | 0.216 | 0.065 | 0.528 | |
number of cases | 421 | 416 | 424 | 167 | 155 | 147 | 346 | 312 | 425 | 421 | 425 | 425 | 327 | |
Numbers of cases represent those for which data for both compared variables were available.
Abbreviations: T=T-classification, N=N-classification, M=M-classification, ECE=extracapsular extension, L=Lymphangiosis, V=vascular tumor emboli, R=resection margin status, HPV=human papilloma virus.