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. 2016 Aug 25;8(9):14794–14805. doi: 10.18632/oncotarget.11605

Figure 1. Endometrial cancer (Case 33) with 19q12 amplification, high Cyclin E1 expression, URI negativity and high 19q12 copy number.

Figure 1

A. Endometrial carcinoma of the clear cell type belonging to type II (HE staining). B. Amplification of 19q12 in a dual-colour ISH (19q12 black signals, reference red signals). C. High Cyclin E1 expression in the tumour cell nuclei. D. Absence of URI expression. E. Intensity ratios (intensity sample/intensity reference) for all chromosome 19-related probes of the OncoScan assay. High copy numbers at 19q12 (CCNE1/URI) locus are indicated by the red arrow.