Table 1. Proportion of FFPE DML identified as DML in FF (positive predictive value) and sensitivity.

Measurements comparing FFPE and FF DML	Δβ-value threshold cutoffs for FFPE DML , FF DML
	0.17, 0.17	0.10, 0.10	0.10, 0.17	0.17, 0.10
Sensitivity (95% CI)	0.29(0.22, 0.38)	0.08(0.07, 0.09)	0.72(0.63, 0.79)	0.02(0.01, 0.02)
Positive Predictive Value* (95% CI)	0.87(0.73, 0.95)	0.49(0.44, 0.53)	0.23(0.19, 0.28)	0.96(0.85, 0.99)

*Proportion of FFPE DML identified in WCHS cohort as DML in FF. Using a Δβ-value threshold of .17 in FFPE a total of 45 DML were identified and using Δβ-value = .10 a total of 410 DML were identified.